U.S. Department of Health & Human Services
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HEAL-funded researchers are comparing the effectiveness of different treatments and treatment combinations for knee osteoarthritis pain.
Published: February 28, 2025
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Researchers hope that by turning off or toning down Nav1.7 activity, they can silence pain-sensing cells and thus relieve pain.
Published: February 18, 2025
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NIH researchers are exploring several promising directions and developments to better support people living with pain
Published: December 9, 2024
Topics:
Novel Targets
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Researchers look for best ways to manage chronic low back pain based on people’s unique experience of pain
Published: October 9, 2024
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Meet the mavericks of pain and substance use disorder research.
Published: August 29, 2024
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HEAL researchers develop roadmap for personalized chronic pain treatments based on patient preferences
Published: July 15, 2024
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Researchers are looking for ways to predict which individuals with pain can recover on their own and which don’t
Published: March 13, 2024
Topics:
Pain Biomarkers
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HEAL SPRINT study aims to identify culprit factors that predict chronic pain in teens
Published: January 9, 2024
Topics:
Pain Biomarkers
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New HEAL research program expands innovation
Published: December 13, 2023
Topics:
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Combinations of animal and human studies explore sleep and circadian rhythms to target opioid use.
Published: December 11, 2023
Topics:
Sleep Dysfunction
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A molecular inventory of pain-sensing nerve cells may lead to more targeted therapies
Published: November 7, 2023
Topics:
Novel Targets
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Human cell model mimics breathing center shut down by overdose
Published: October 11, 2023
Topics:
New Drugs/Screening Tools
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Finding the Best Treatment for Individual Patients
Published: September 27, 2023
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Access to real-time data helps treatment providers and harm reduction organizations
Published: August 17, 2023
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Connecting Pain Scientists Through the PURPOSE Network
Published: August 1, 2023
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Exploring family support as a way to protect and manage chronic pain for older African Americans.
Published: May 25, 2023
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The Restoring Joint Health and Function to Reduce Pain (RE-JOIN) Consortium
Published: May 18, 2023
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HEAL-funded researchers work together with D.C. communities hard-hit by the opioid crisis
Published: May 12, 2023
Topics:
NIDA CTN
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Treating the brain with non-invasive stimulation
Published: April 26, 2023
Topics:
Small Business Programs
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Can a single dose of ketamine prevent chronic pain and depression after mastectomy?
Published: April 3, 2023
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HEAL researchers are creating new tools in the toolbox in the quest to help patients with back pain. Learn about "microgels."
Published: March 23, 2023
Topics:
Non-addictive Therapies
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Examining the Role of Pain Coping Skills
Published: February 28, 2023
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Dr. Allan Basbaum explains why interacting with pain patients is important for basic scientists.
Published: February 2, 2023
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Can resetting brain circuits help people find recovery?
Published: November 15, 2022
Topics:
Drug Development
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Seeking sustainable models of integrated care
Published: October 27, 2022
Topics:
Collaborative Care
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Successful approaches to research partnerships with patients and communities
Published: October 6, 2022
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Questions and answers with Amy Goldstein and Barbara Oudekerk
Published: September 7, 2022
Topics:
Adolescent Prevention
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Targeting the causes of opioid misuse and addiction
Published: September 7, 2022
Topics:
Adolescent Prevention
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HEAL prevention research targets systems for sustainability
Published: September 7, 2022
Topics:
Adolescent Prevention
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Better Sleep Eases Opioid Withdrawal and Cuts Drug Craving
Published: July 6, 2022
Topics:
Sleep Dysfunction
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“Artificial muscle” may help prevent back problems
Published: June 6, 2022
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Understanding how environmental exposures affect infant and child brain development
Published: April 13, 2022
Topics:
HBCD Study
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An implanted device that detects an overdose and administers naloxone
Published: March 21, 2022
Topics:
Drug Development
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Innovative research for people with chronic pain and risky opioid use or opioid use disorder
Published: February 7, 2022
Topics:
IMPOWR and MIRHIQL
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New treatment options on the horizon for pain associated with sickle cell disease
Published: January 26, 2022
Topics:
PRISM, Device Discovery
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Tissue chip-based model screens potential pain medications faster
Published: December 10, 2021
Topics:
New Drugs/Screening Tools
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New personalized text-messaging app may make it easier for people with opioid use disorder to continue buprenorphine treatment
Published: November 22, 2021
Topics:
Behavioral Research
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HEAL-funded researchers are investigating the role of sleep deficiency in opioid use disorder and relapse risk
Published: October 28, 2021
Topics:
Sleep Dysfunction
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Research strategy targets craving to treat addiction
Published: October 8, 2021
Topics:
Drug Development
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HEAL-funded researchers develop tools for primary care providers to identify and help patients at risk of suicide
Published: September 28, 2021
Topics:
Collaborative Care
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NIH HEAL Initiative research aims to help people stay in recovery long-term
Published: September 28, 2021
Topics:
RRN
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Introducing early career investigators involved in the NIH HEAL Initiative
Published: September 14, 2021
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Connecting people with opioid use disorder with treatment
Published: August 30, 2021
Topics:
NIDA CTN
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Everyone wins when we dismantle stigma
Published: August 2, 2021
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HEAL researchers combine antidepressants and physical therapy
Published: July 6, 2021
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Turning tarantula venom into a non-opioid treatment for pain
Published: May 7, 2021
Topics:
Non-addictive Therapies
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HEAL-funded research team is using the power of play to prevent opioid misuse in youth
Published: March 9, 2021
Topics:
Adolescent Prevention
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Helping vulnerable populations acquire treatment for low back pain
Published: February 23, 2021
Topics:
PRISM, Advancing Health Equity
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Using bone glue to treat pain from wisdom-tooth extractions
Published: February 9, 2021
Topics:
Small Business Programs
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Toward personalized care for people treated with dialysis
Published: January 28, 2021
Topics:
Pain & Dialysis
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NIH HEAL research aims to address stigma among healthcare providers
Published: January 21, 2021
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Questions and answers with the HEAL Patient Engagement Working Group
Published: January 7, 2021
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Can immersive experiences provide relief by distracting patients from pain?
Published: December 22, 2020
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Re-envisioning how the criminal justice system responds to the opioid crisis
Published: November 5, 2020
Topics:
JCOIN
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Communities and scientists join forces to save lives from opioid use disorder
Published: October 19, 2020
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Community members are working to save lives from opioid-related overdoses
Published: October 18, 2020
Topics:
HEALing Communities
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A small company is developing a new way to create a safe extended-release pain medication
Published: October 14, 2020
Topics:
Small Business Programs
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A team of scientists at Knopp Biosciences LLC, is innovating treatments to manage neuropathic pain by aiming at its source — hyperactive nerve cells.
Published: October 14, 2020
Topics:
Non-addictive Therapies
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An NIH HEAL Initiative® research team is searching for new targets for non-addictive pain treatments
Published: October 5, 2020
Topics:
Novel Targets
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The NIH HEAL Initiative wants to learn from examples of successful strategies used by researchers that meet patients where they are and invite them to join the research process. Email [email protected]
Published: August 19, 2020
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From surgery and drugs to cell-based therapies, researchers will test innovative, non-addictive approaches for treating pain.
Published: August 5, 2020
Topics:
EPPIC-Net
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The NIH HEAL Initiative supports research that looks at the relationship of prenatal exposure of opioids on brain function in infants. Research also studies the role that prenatal exposure to opioids might play in the emergence of cognitive and behavioral issues.
Published: July 29, 2020
Topics:
HBCD Study
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Project aims to improve pain relief while supporting treatment for opioid use disorder and long-term recovery.
Published: July 27, 2020
Topics:
Behavioral Research
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Studies in animals test the effects of sleep deficiency in opioid misuse and addiction.
Published: July 24, 2020
Topics:
Sleep Dysfunction
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Testing medication-based treatment for opioid use disorder for the long-term.
Published: July 24, 2020
Topics:
Medication Treatment
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Support system model encourages young adults to access and continue medication-based treatment to achieve long-term recovery.
Published: July 21, 2020
Topics:
Behavioral Research
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With new technology, researchers can understand the effects of repeated overdoses and test new treatments.
Published: July 16, 2020
Topics:
New Drugs/Screening Tools
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NIH HEAL Initiative research seeks better long-term outcomes for babies with neonatal opioid withdrawal syndrome, or NOWS.
Published: June 12, 2020
Topics:
ACT NOW
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Researchers develop a new type of injectable electrode for neuromodulation therapy.
Published: June 10, 2020
Topics:
Device Discovery
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Scientists identified a group of neurons in mice that blunt pain within the brain. Such neurons could be promising targets for new non-addictive therapies for chronic pain.
Published: June 4, 2020
Topics:
Novel Targets
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A computer model may be able to inspire new insights and treatments.
Published: June 2, 2020
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Can a team-based approach improve treatment for people with both opioid use disorder and mental health conditions?
Published: May 20, 2020
Topics:
Collaborative Care
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Research explores the integration of medication-based treatment with the healing traditions of American Indian and Alaska Native communities.
Published: May 15, 2020
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NIH HEAL Initiative study aims to improve outcomes for mothers after cesarean deliveries.
Published: May 5, 2020
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An NIH HEAL Initiative project is studying whether a telemedicine system to connect women with treatment providers and peer support before their release from jail can help the women stay in treatment and recover from opioid use disorder once in the community.
Published: April 29, 2020
Topics:
JCOIN
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Research funded by the NIH HEAL Initiative® is studying whether a web-based program can help people cope with chronic pain.
Published: April 17, 2020
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An NIH HEAL Initiative® study is using a computer simulation program with virtual patients to help real doctors understand their biases when assessing their patients’ risk of opioid misuse.
Published: April 15, 2020
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The NIH HEAL Initiative® — a research effort led by the National Institutes of Health (NIH) — aims to prevent opioid overdose deaths and improve how we understand and treat both pain and opioid addiction.
Published: April 6, 2020
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Doctors can’t predict how much pain a person will feel after surgery, making tailored treatments difficult. One NIH HEAL Initiative researcher hopes to develop a blood test to predict how sensitive people will be to pain.
Published: March 31, 2020
Topics:
Pain Biomarkers
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The NIH HEAL Initiative® is funding a project to develop a long-lasting implant to release medication for opioid use disorder to help patients stay on treatment and achieve long-term recovery.
Published: March 24, 2020
Topics:
Drug Development
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HEAL challenged researchers to consider stigma when planning ways to address the opioid crisis.
Published: March 10, 2020