Funded Projects

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Project # Project Title Research Focus Area Research Program Administering IC Institution(s) Investigator(s) Location(s) Year Awarded
4U24NS113784-02
University of Rochester Hub and Spokes for the EPPIC Network - Specialized Clinical Center Clinical Research in Pain Management Early Phase Pain Investigation Clinical Network (EPPIC-Net) NINDS UNIVERSITY OF ROCHESTER GEWANDTER, JENNIFER Rochester, NY 2024
NOFO Title: HEAL Initiative: Early Phase Pain Investigation Clinical Network - Specialized Clinical Centers (U24 Clinical Trial Not Allowed)
NOFO Number: RFA-NS-19-025
1U01HD116260-01
Optimizing Pain Treatment In Children On Mechanical ventilation (OPTICOM) Clinical Research in Pain Management NICHD CORNELL UNIVERSITY TRAUBE, CHANI (contact); BELL, MICHAEL J; HOLUBKOV, RICHARD New York, NY 2024
NOFO Title: HEAL Initiative: HEAL KIDS (Knowledge, Innovation and Discovery Studies) Pain: Acute Pain Clinical Trials Program (U01 Clinical Trial Required)
NOFO Number: RFA-HD-24-011
1R61NS138215-01
Developing equilibrative nucleoside transporter inhibitors as non-opioid pain therapeutics Preclinical and Translational Research in Pain Management Development and Optimization of Non-Addictive Therapies to Treat Pain NINDS DUKE UNIVERSITY LEE, SEOK-YONG (contact); HONG, JIYONG ; JI, RU-RONG Durham, NC 2024
NOFO Title: HEAL Initiative: Planning Studies for Initial Analgesic Development [Small Molecules and Biologics] (R61 Clinical Trial Not Allowed)
NOFO Number: RFA-NS-21-029
1R18EB036591-01
Transspinal Magnetic Stimulation for the Treatment of Neuropathic Pain Preclinical and Translational Research in Pain Management Translating Discoveries into Effective Devices to Treat Pain NIBIB MASSACHUSETTS GENERAL HOSPITAL BONMASSAR, GIORGIO Boston, MA 2024
NOFO Title: HEAL Initiative: Translational Development of Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)
NOFO Number: RFA-EB-22-002
3UG3NS115637-03S1
Clinical Translation of Ultrasonic Ketamine Uncaging for Non-Opioid Therapy of Chronic Pain Training the Next Generation of Researchers in HEAL NINDS STANFORD UNIVERSITY AIRAN, RAAG D (contact); WILLIAMS, NOLAN R Stanford, CA 2024
NOFO Title: Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed)
NOFO Number: PA-23-189
3U24TR004315-03S1
HEAL ERN: Data Coordinating Resource Center Clinical Research in Pain Management Pain Management Effectiveness Research Network (ERN) NCATS UNIVERSITY OF UTAH WATT, KEVIN M (contact); DWYER, JAMIE P; SWARD, KATHERINE ANN Salt Lake City, UT 2024
NOFO Title: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
NOFO Number: PA-20-272
1DP2AR085223-01
Regulation of inflammation by nociception Training the Next Generation of Researchers in HEAL NIAMS SCRIPPS RESEARCH INSTITUTE MENDOZA, ALEJANDRA La Jolla, CA 2024
NOFO Title: Emergency Awards: HEAL Initiative- New Innovator Award (DP2 Clinical Trial Not Allowed)
NOFO Number: RFA-TR-23-011
1R21NS136077-01
The involvement of GPR37L1 on a chronic migraine-like state Preclinical and Translational Research in Pain Management Discovery and Validation of Novel Targets for Safe and Effective Treatment of Pain NINDS FLORIDA ATLANTIC UNIVERSITY CIPPITELLI, ANDREA (contact); ROBISHAW, JANET D Boca Raton, FL 2024
NOFO Title: Emergency Awards: HEAL Initiative-Early-Stage Discovery of New Pain and Opioid Use Disorder Targets Within the Understudied Druggable Proteome (R21 Clinical Trial Not Allowed)
NOFO Number: RFA-TR-23-015
1R90DE034698-01
University of Michigan HEAL PAIN Cohort Program Training the Next Generation of Researchers in HEAL NIDCR UNIVERSITY OF MICHIGAN CLAUW, DANIEL J (contact); KIDWELL, KELLEY MCLAIN; WIENS, JENNA Ann Arbor, MI 2024
NOFO Title: HEAL Initiative Partnerships to Advance INterdisciplinary (PAIN) Training in Clinical Pain Research: The HEAL PAIN Cohort Program (T90/R90 Independent Clinical Trial Not Allowed)
NOFO Number: RFA-NS-24-015
1T90NR021683-01
PRomoting Excellence through Pain and Addiction Research Enhancement (PREPARE) Training the Next Generation of Researchers in HEAL NINR WASHINGTON UNIVERSITY IN ST. LOUIS GOODIN, BUREL R Saint Louis, MO 2024
NOFO Title: HEAL Initiative Partnerships to Advance INterdisciplinary (PAIN) Training in Clinical Pain Research: The HEAL PAIN Cohort Program (T90/R90 Independent Clinical Trial Not Allowed)
NOFO Number: RFA-NS-24-015
1R01AR085334-01
Psychometric Reliability and Validity for Behavioral Metrics of Osteoarthritic Pain in Horses Preclinical and Translational Research in Pain Management NIAMS UNIVERSITY OF FLORIDA ALLEN, KYLE D (contact); BIEDRZYCKI, ADAM H; BROOKS, SAMANTHA A; CRUZ-ALMEIDA, YENISEL Gainesville, FL 2024
NOFO Title: HEAL Initiative: Development and Validation of Non-Rodent Mammalian Models of Pain(R01 Clinical Trial Not Allowed)
NOFO Number: RFA-NS-22-070
1R01DE033674-01
Targeting Schwann cell dysfunction and repair signaling in chemotherapy induced painful peripheral neuropathy Preclinical and Translational Research in Pain Management NIDCR NEW YORK UNIVERSITY YE, YI (contact); CAMPANA, WENDY M New York, NY 2024
NOFO Title: HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)
NOFO Number: RFA-NS-22-034
4U24NS115708-02
University of Pittsburgh Hub and Spoke Pain Clinical Trial Network Clinical Research in Pain Management Early Phase Pain Investigation Clinical Network (EPPIC-Net) NINDS UNIVERSITY OF PITTSBURGH WASAN, AJAY D (contact); ALTER, BENEDICT J Pittsburgh, PA 2024
NOFO Title: HEAL Initiative: Early Phase Pain Investigation Clinical Network - Specialized Clinical Centers (U24 Clinical Trial Not Allowed)
NOFO Number: RFA-NS-22-034
1UG3NS135350-01A1
A novel oral immunotherapy for chronic visceral pain of irritable bowel syndrome Preclinical and Translational Research in Pain Management Development and Optimization of Non-Addictive Therapies to Treat Pain NINDS FZATA, INC. YANG, ZHIYONG (contact); FENG, HANPING ; WEI, FENG Halethorpe, MD 2024
NOFO Title: HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
NOFO Number: RFA-NS-21-010
1U19NS138975-01
Developing small molecules to engage an analgesic GPCR in pain unpleasantness neural circuits Preclinical and Translational Research in Pain Management Development and Optimization of Non-Addictive Therapies to Treat Pain NINDS UNIVERSITY OF NORTH CAROLINA SCHERRER, GREGORY (contact); AUBE, JEFFREY ; SCHNITZER, MARK J Chapel Hill, NC 2024
NOFO Title: HEAL Initiative: Team Research for Initial Translational Efforts in Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] (U19 Clinical Trial Not Allowed)
NOFO Number: RFA-NS-22-052
1R61NS133264-01A1
Validation of a Translational Model of Chronic Discogenic Low Back Pain Preclinical and Translational Research in Pain Management NINDS ARIZONA STATE UNIVERSITY WACHS, REBECCA ANN (contact); KING, TAMARA E Tempe, AZ 2024
NOFO Title: Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)
NOFO Number: PAR-21-123
5UH3AT010739-04
Pragmatic Trial of Acupuncture for Chronic Low Back Pain in Older Adults Clinical Research in Pain Management Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing (PRISM) NCCIH KAISER FOUNDATION RESEARCH INSTITUTE DEBAR, LYNN L (contact); COOK, ANDREA J Oakland, CA 2023
NOFO Title: HEAL Initiative: Pragmatic Randomized Controlled Trial of Acupuncture for Management of Chronic Low Back Pain in Older Adults (UG3/UH3 Clinical Trial Required)
NOFO Number: RFA-AT-19-005
3UC2AR082200-01S1
Neuronal anatomy, connectivity, and phenotypic innervation of the knee joint Preclinical and Translational Research in Pain Management Restoring Joint Health and Function to Reduce Pain (RE-JOIN) NIAMS BAYLOR COLLEGE LEE, BRENDAN (contact); ARENKIEL, BENJAMIN R; RAY, RUSSELL S; WYTHE, JOSHUA D Houston, TX 2024
NOFO Title: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
NOFO Number: PA-20-272
1R21AG086147-01
Binding NF-_B essential modulator (NEMO) to Treat Surgical Pain Preclinical and Translational Research in Pain Management Discovery and Validation of Novel Targets for Safe and Effective Treatment of Pain NIA STANFORD UNIVERSITY GROSS, ERIC RICHARD Stanford, CA 2024
NOFO Title: Emergency Awards: HEAL Initiative-Early-Stage Discovery of New Pain and Opioid Use Disorder Targets Within the Understudied Druggable Proteome (R21 Clinical Trial Not Allowed)
NOFO Number: RFA-TR-23-010
1K99HD115239-01
Neuroimmune communication as a driver of lesion formation and macrophage colonization of the omentum in endometriosis-associated pain Training the Next Generation of Researchers in HEAL NICHD BOSTON CHILDREN’S HOSPITAL FATTORI, VICTOR Boston, MA 2024
NOFO Title: HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed)
NOFO Number: RFA-NS-22-025
1R90NS143074-01
Mass General Brigham Interdisciplinary Clinical Pain Research Training Program Training the Next Generation of Researchers in HEAL NINDS BRIGHAM AND WOMEN’S HOSPITAL EDWARDS, ROBERT R (contact); SCHREIBER, KRISTIN Boston, MA 2024
NOFO Title: HEAL Initiative Partnerships to Advance INterdisciplinary (PAIN) Training in Clinical Pain Research: The HEAL PAIN Cohort Program (T90/R90 Independent Clinical Trial Not Allowed)
NOFO Number: RFA-NS-24-015
4R33AG081034-02
Addressing the chronic pain epidemic among older adults in underserved community center; The GetActive+ study. Clinical Research in Pain Management Advancing Health Equity in Pain Management NIA MASSACHUSETTS GENERAL HOSPITAL VRANCEANU, ANA-MARIA (contact); RITCHIE, CHRISTINE S Boston, MA 2024
NOFO Title: HEAL Initiative: Advancing Health Equity in Pain Management (R61/R33 Clinical Trial Required)
NOFO Number: RFA-NS-22-002
1R43HL172316-01
A Novel Aerosolization and Inhalation Platform for the Pulmonary Delivery of Anti-inflammatory Agents to Distal Airways for the Enhanced Pain Management in Chronic Obstructive Pulmonary Disease (COPD) Clinical Research in Pain Management Discovery and Validation of Biomarkers, Endpoints, and Signatures for Pain Conditions NHLBI SCIENTIFIC HORIZONS CONSULTING, LLC GAO, XIANG Irvine, CA 2024
NOFO Title: HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)
NOFO Number: RFA-NS-23-006
1RF1NS136108-01
Cellular Mechanisms and Therapeutic Potential of NR4A1 in Pain Resolution Preclinical and Translational Research in Pain Management Discovery and Validation of Novel Targets for Safe and Effective Treatment of Pain NINDS UNIVERSITY OF CINCINNATI BERTA, TEMUGIN Cincinnati, OH 2024
NOFO Title: HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)
NOFO Number: RFA-NS-22-034
1U01HD116253-01
Efficacy of intravenous sub-dissociative ketamine versus intravenous morphine in children with acute pain. Clinical Research in Pain Management NICHD COLUMBIA UNIVERSITY TSZE, DANIEL SING-KWONG (contact); DRENDEL, AMY L New York, NY 2024
NOFO Title: HEAL Initiative: HEAL KIDS (Knowledge, Innovation and Discovery Studies) Pain: Acute Pain Clinical Trials Program (U01 Clinical Trial Required)
NOFO Number: RFA-HD-24-011