Funded Projects

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Project # Project Title Research Focus Area Research Program Administering IC Institution(s) Investigator(s) Location(s) Year Awarded
2SB1AT011593-04
Commercialization of a Behavioral Digital Health Program for Individuals with Chronic Pain Cross-Cutting Research Small Business Programs NCCIH 2MORROW, INC. MASTERSON, JO (contact); WATERS, DEANNA Kirkland, WA 2024
NOFO Title: HEAL Commercialization Readiness Pilot (CRP) Program: Embedded Entrepreneurs for Small Businesses in Pain Management (SB1 Clinical Trial Not Allowed)
NOFO Number: PAR-23-069
1R90HD118650-01
Interdisciplinary research training in maternal and childhood pain Training the Next Generation of Researchers in HEAL NICHD STANFORD UNIVERSITY SIMONS, LAURA E Stanford, CA 2024
NOFO Title: HEAL Initiative Partnerships to Advance INterdisciplinary (PAIN) Training in Clinical Pain Research: The HEAL PAIN Cohort Program (T90/R90 Independent Clinical Trial Not Allowed)
NOFO Number: RFA-NS-24-015
1T90NS138001-01
Mass General Brigham Interdisciplinary Clinical Pain Research Training Program Training the Next Generation of Researchers in HEAL NINDS BRIGHAM AND WOMEN’S HOSPITAL EDWARDS, ROBERT R (contact); SCHREIBER, KRISTIN Boston, MA 2024
NOFO Title: HEAL Initiative Partnerships to Advance INterdisciplinary (PAIN) Training in Clinical Pain Research: The HEAL PAIN Cohort Program (T90/R90 Independent Clinical Trial Not Allowed)
NOFO Number: RFA-NS-24-015
1R01AR085335-01
Innovative modeling of the biopsychosocial model in animals: Validation of outcomes for assessing emotional and cognitive domains affected by naturally-occurring chronic pain in dogs Preclinical and Translational Research in Pain Management NIAMS NORTH CAROLINA STATE UNIVERSITY GRUEN, MARGARET ELIZABETH (contact); HARE, BRIAN ; LASCELLES, DUNCAN Raleigh, NC 2024
NOFO Title: HEAL Initiative: Development and Validation of Non-Rodent Mammalian Models of Pain(R01 Clinical Trial Not Allowed)
NOFO Number: RFA-NS-22-070
1RF1AG088052-01
Validation of neuronal senescence as a target for chronic pain in aging Preclinical and Translational Research in Pain Management Discovery and Validation of Novel Targets for Safe and Effective Treatment of Pain NIA STANFORD UNIVERSITY TAWFIK, VIVIANNE L Stanford, CA 2024
NOFO Title: HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)
NOFO Number: RFA-NS-22-034
4U24NS115714-02
California Clinical and Translational Pain Research Consortium Clinical Research in Pain Management Early Phase Pain Investigation Clinical Network (EPPIC-Net) NINDS UNIVERSITY OF CALIFORNIA SAN DIEGO WALLACE, MARK S La Jolla, CA 2024
NOFO Title: HEAL Initiative: Early Phase Pain Investigation Clinical Network - Specialized Clinical Centers (U24 Clinical Trial Not Allowed)
NOFO Number: RFA-NS-22-034
4UH3NS127943-02
Oral N2O Therapy in Treating Acute Vaso-Occlusive Pain in Sickle Cell Disease Preclinical and Translational Research in Pain Management Development and Optimization of Non-Addictive Therapies to Treat Pain NINDS HILLHURST BIOPHARMACEUTICALS, INC. GOMPERTS, EDWARD (contact); BELCHER, JOHN D; SIMONE, DONALD Montrose, CA 2024
NOFO Title: HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
NOFO Number: RFA-NS-21-010
1R61AT012270-01A1
Development and Clinical Translation of RPBM for Quantitative Assessment of Myofascial Pain Preclinical and Translational Research in Pain Management Discovery and Validation of Biomarkers, Endpoints, and Signatures for Pain Conditions NCCIH CORNELL UNIVERSITY KIM, SUNGHEON GENE (contact); FIEREMANS, ELS ; NOVIKOV, DMITRY S; REEVE, GWENDOLYN New York, NY 2024
NOFO Title: HEAL Initiative: Toward Developing Quantitative Imaging and Other Relevant Biomarkers of Myofascial Tissues for Clinical Pain Management (R61/R33, Clinical Trial Required)
NOFO Number: RFA-AT-24-003
1R61NS133274-01A1
A novel platform for the discovery and characterization of migraine therapies Preclinical and Translational Research in Pain Management NINDS UNIVERSITY OF CALIFORNIA LOS ANGELES CHARLES, ANDREW C (contact); PRADHAN, AMYNAH AMIR ALI Los Angeles, CA 2024
NOFO Title: Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)
NOFO Number: PAR-21-123
3K12NS130673-02S1
University of Michigan (UM) HEAL Initiative National K12 Clinical Pain Career Development Program (UM-HCPDP) Training the Next Generation of Researchers in HEAL NINDS UNIVERSITY OF MICHIGAN WILLIAMS, DAVID A (contact); CLAUW, DANIEL J; HARTE, STEVEN EDWARD Ann Arbor, MI 2024
NOFO Title: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
NOFO Number: PA-20-272
3UH3CA261067-05S1
Optimizing the use of ketamine to reduce chronic postsurgical pain Clinical Research in Pain Management Pain Management Effectiveness Research Network (ERN) NCI NEW YORK UNIVERSITY WANG, JING (contact); DOAN, LISA New York, NY 2024
NOFO Title: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
NOFO Number: PA-20-272
1R21DE033639-01
Role of Understudied aGPCRs in Orofacial Neuropathic Pain Preclinical and Translational Research in Pain Management Discovery and Validation of Novel Targets for Safe and Effective Treatment of Pain NIDCR UNIVERSITY OF FLORIDA CAUDLE, ROBERT M (contact); AYAZ, BASAK Gainesville, FL 2024
NOFO Title: Emergency Awards: HEAL Initiative-Early-Stage Discovery of New Pain and Opioid Use Disorder Targets Within the Understudied Druggable Proteome (R21 Clinical Trial Not Allowed)
NOFO Number: RFA-TR-23-011
1RM1NS135283-01A1
IMPETUS: Integrated Mechanisms, Phenotypes, and Translational Underpinnings of Chronic Pain after Surgery Preclinical and Translational Research in Pain Management Integrated Basic and Clinical Team-Based Research in Pain NINDS WASHINGTON UNIVERSITY IN ST. LOUIS HAROUTOUNIAN, SIMON (contact); CREED, MEAGHAN C; LU, CHENYANG ; RODEBAUGH, THOMAS L; SHEPHERD, ANDREW JOHN; SINHA, PRATIK Saint Louis, MO 2024
NOFO Title: HEAL Initiative Integrated Basic and Clinical Team-based Research in Pain(RM1 Clinical Trial Optional)
NOFO Number: RFA-NS-22-069
1T90AR085527-01
University of Florida Partnerships Across Interdisciplinary Networks: Training through Engineering, epidemiology & Addiction Medicine (UF PAIN TEAM) Training the Next Generation of Researchers in HEAL NIAMS UNIVERSITY OF FLORIDA CRUZ-ALMEIDA, YENISEL (contact); ALLEN, KYLE D Gainesville, FL 2024
NOFO Title: HEAL Initiative Partnerships to Advance INterdisciplinary (PAIN) Training in Clinical Pain Research: The HEAL PAIN Cohort Program (T90/R90 Independent Clinical Trial Not Allowed)
NOFO Number: RFA-NS-24-015
4R33DK135406-02
PAINED: Project Addressing INequities in the Emergency Department Clinical Research in Pain Management Advancing Health Equity in Pain Management NIDDK CHILDREN’S RESEARCH INSTITUTE GOYAL, MONIKA KUMARI Washington, DC 2024
NOFO Title: HEAL Initiative: Advancing Health Equity in Pain Management (R61/R33 Clinical Trial Required)
NOFO Number: RFA-NS-22-002
1R43MH135524-01A1
Training Psychologists and Nurse Practitioners in the Use of an Evidence-Based Online Pain Self-Management Program: Leveraging the Power of Expert Guidance and Telehealth Clinical Research in Pain Management Discovery and Validation of Biomarkers, Endpoints, and Signatures for Pain Conditions NIMH GOALISTICS, LLC RUEHLMAN, LINDA SUE Tempe, AZ 2024
NOFO Title: HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)
NOFO Number: RFA-NS-23-006
1UG3NS138882-01
Developing AI-Driven Pain Intensity and Pain Sensitization Biomarker Signatures to Optimize Neonatal Pain Management Clinical Research in Pain Management Discovery and Validation of Biomarkers, Endpoints, and Signatures for Pain Conditions NINDS UNIVERSITY OF SOUTH FLORIDA SUN, YU (contact); ANAND, KANWALJEET S; HO, THAO ; PRESCOTT, STEPHANIE Tampa, FL 2024
NOFO Title: HEAL Initiative: Discovery of Biomarkers and Biomarker Signatures to Facilitate Clinical Trials for Pain Therapeutics (UG3/UH3 Clinical Trial Optional)
NOFO Number: RFA-NS-24-018
1U01HD116257-01
Implementing and Personalizing Best-In-Class Opioid-sparing Pain Management for Major Inpatient Surgeries in Children Clinical Research in Pain Management NICHD UNIVERSITY OF PITTSBURGH SADHASIVAM, SENTHILKUMAR (contact); CHIDAMBARAN, VIDYA Pittsburgh, PA 2024
NOFO Title: HEAL Initiative: HEAL KIDS (Knowledge, Innovation and Discovery Studies) Pain: Acute Pain Clinical Trials Program (U01 Clinical Trial Required)
NOFO Number: RFA-HD-24-011
1R61NS136307-01
Development of PAC1 receptor antagonists for the treatment of Headache Disorders Preclinical and Translational Research in Pain Management Development and Optimization of Non-Addictive Therapies to Treat Pain NINDS WASHINGTON UNIVERSITY IN ST. LOUIS PRADHAN, AMYNAH AMIR ALI (contact); KATRITCH, VSEVOLOD ; MAJUMDAR, SUSRUTA Saint Louis, MO 2024
NOFO Title: HEAL Initiative: Planning Studies for Initial Analgesic Development [Small Molecules and Biologics] (R61 Clinical Trial Not Allowed)
NOFO Number: RFA-NS-21-029
1R61EB036967-01
Imaging of pain sources in myofascial pain syndrome Preclinical and Translational Research in Pain Management Discovery and Validation of Biomarkers, Endpoints, and Signatures for Pain Conditions NIBIB STANFORD UNIVERSITY GOLD, GARRY E (contact); KOGAN, FELIKS Stanford, CA 2024
NOFO Title: HEAL Initiative: Toward Developing Quantitative Imaging and Other Relevant Biomarkers of Myofascial Tissues for Clinical Pain Management (R61/R33, Clinical Trial Required)
NOFO Number: RFA-AT-24-003
3U01DA055349-04S1
10/24 Healthy Brain and Child Development National Consortium Training the Next Generation of Researchers in HEAL NIDA OKLAHOMA STATE UNIVERSITY CENTER FOR HEALTH SCIENCES CROFF, JULIE MAY (contact); HAYS-GRUDO, JENNIFER ; MORRIS, AMANDA S Tulsa, OK 2024
NOFO Title: Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed)
NOFO Number: PA-21-071
3U24NS113844-05S2
EPPIC-NET DCC - Supplement Clinical Research in Pain Management Early Phase Pain Investigation Clinical Network (EPPIC-Net) NINDS NEW YORK UNIVERSITY TROXEL, ANDREA B (contact); YU, CHANG New York, NY 2024
NOFO Title: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
NOFO Number: PA-20-272
4R33NS113329-02
Discovery of Biomarker Signatures Prognostic for Neuropathic Pain after Acute Spinal Cord Injury Preclinical and Translational Research in Pain Management Translating Discoveries into Effective Devices to Treat Pain NINDS UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON HERGENROEDER, GEORGENE W Houston, TX 2024
NOFO Title: Discovery of Biomarkers, Biomarker Signatures, and Endpoints for Pain (R61/R33 Clinical Trial Optional)
NOFO Number: RFA-NS-18-041
1R21NS136075-01
Role of Scn1b in Susceptibility to Neuropathic Pain Preclinical and Translational Research in Pain Management Discovery and Validation of Novel Targets for Safe and Effective Treatment of Pain NINDS UNIVERSITY OF CALIFORNIA BERKELEY LUMPKIN, ELLEN A (contact); BAUTISTA, DIANA MICHELE Berkeley, CA 2024
NOFO Title: Emergency Awards: HEAL Initiative-Early-Stage Discovery of New Pain and Opioid Use Disorder Targets Within the Understudied Druggable Proteome (R21 Clinical Trial Not Allowed)
NOFO Number: RFA-TR-23-014
1R90DA062893-01
University of Utah Program to Provide Pain Research Knowledge (UP3RK) Training the Next Generation of Researchers in HEAL NIDA UNIVERSITY OF UTAH FRITZ, JULIE M Salt Lake City, UT 2024
NOFO Title: HEAL Initiative Partnerships to Advance INterdisciplinary (PAIN) Training in Clinical Pain Research: The HEAL PAIN Cohort Program (T90/R90 Independent Clinical Trial Not Allowed)
NOFO Number: RFA-NS-24-015